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pentobarbital will decrease the extent or influence of etonogestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.Keep an eye on Carefully (two)pentobarbital will decrease the extent or effect of suvorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Sturdy CYP3A4 inducers may lower